A Solution for Medically Supervised Fecal Microbiota Transplants.
FMT Solution was founded to provide high-quality medically supervised fecal microbiota transplants (FMT) for autism and the diverse range of symptoms that come with being on the spectrum.
FMT Solution is the first and only clinic in the world to duplicate the treatment protocol developed by Dr. James Adam and his team at Arizona State University. At 18 weeks, they observed an 80% improvement from baseline in digestive related symptoms as well as a 25% improvement in autism-related symptoms after only 8 weeks of daily FMT treatment. At a two year follow up, they observed the 80% improvement in digestive symptoms maintained and a further 20% improvement in autism-related symptoms was reported, for a total of nearly 50% improvement from the baseline of the study. See the initial study here along with the two year follow up study here.
We are dedicated to supporting children and families affected by autism to improve their quality of life as well as push for more research and the eventual approval by individual countries regulatory and approval bodies for the inclusion of FMT as a treatment for autism worldwide.
Discover more by reviewing this website and looking through the FAQs section to learn more about FMT specifically and to determine if your child and/or your patients are a fit for this progressive therapy.
Meet the team.
FMT Solution has assembled a team of experts to help ensure that you are informed about the treatment, as well, that you feel supported, understood and confident as you move through the decision making process and in arranging the logistics of your arrival and departure from Mexico. Once in Mexico, we will continue to provide support and guidance as needed to ensure the safe and effective delivery of the treatment. Additionally, we provide follow up support in conjunction with your health care providers over the full 16 weeks of treatment.
Jason Klop has been working in the field of digestive health and microbiome restoration for many years and during this time focused on conditions that were not responding to pharmaceutical interventions such as Irritable Bowel Syndrome (IBS), Crohn’s, Ulcerative Colitis and Small Intestinal Bacterial Overgrowth (SIBO). Jason has learned that the foundation for all health lies in the gut and through his extensive experience, he has broadened his focus to include treating children with autism and autism-related symptoms, with a focus on digestive health and microbiome restoration.
Dr. Santiago Sandoval, MD
Dr. Sandoval is a medical doctor with a Master’s in hospital administration who strongly believes that to be a good doctor, you have to not only treat the disease but also the whole person.
Dr. Sandoval loves to give back to the community and help those in need. For much of his life, he has dedicated himself to helping underprivileged children through his foundation and medical brigades. During his free time, you can find him spending time with family, friends, playing basketball and reading books.
Marlene Maljaars is a patient care coordinator here at FMT Solution and has been working alongside Jason Klop for the last 3 years to make sure that all attendees questions are answered and all necessary documentation is completed. Marlene ensures that your experience from start to finish is smooth and effortless.
Remie graduated as a nurse from Sonora School of Nursing where she got specialty training in the field of neonatology at a children’s hospital. Through her storied career, she has spent many years in pediatric intensive care, as well as working in nephrology and gastroenterology units.
Remie’s vast experience in pediatrics makes her a perfect candidate to administer the FMT treatments at the retreats and has been assisting in administering enemas for all retreat attendees since FMT Solution began focusing on offering FMT for children with autism.
Currently, medically supervised FMT is not available in the United States or Canada except for C difficile infections resistant to standard antibiotic treatments. As such, FMT Solution has partnered with medical professionals in Baja California, Mexico to be able to deliver this progressive therapy.
Next available dates:
Jan 25 – 29, 2021 (Mexico – sold out)
February 15 – 19, 2021 (Mexico)
March 22 – 26, 2021 (Mexico)
FMT Solution does not provide food for attendees. However, when transporting from San Diego to Mexico our drivers can stop at Whole Foods so you can pick up enough food for the week.
There are many quality restaurants within walking distance from the hotel and an organic food delivery option should you need more options.
What should I expect when there?
Guidance on your specific pre-FMT treatment to optimize your child’s gut and overall health so they better respond to the treatment. Nearly always includes antimicrobial or antibiotic treatment.
Day 1: Arrive to San Diego + Transport to Rosarito Beach Hotel
Day 2: Medical Consult + Bowel cleanse.
Day 3: First FMT treatment (liquid group receives enema), capsule group takes 35 capsules throughout the day for the “loading dose”.
Day 4: Second FMT treatment (liquid group receives enema), capsule group takes 35 capsules throughout the day for the “loading dose”.
Day 5: Transport back to San Diego for the trip home. The liquid group begins maintenance dose and the capsule group begins taking one capsule per day.
A further 15 weeks of “at home” treatment will accompany you home with the appropriate storage supplies for the remainder of the treatment.
Follow up support with bi-weekly meetings to tailor dietary and lifestyle interventions.
Baja California, Mexico (1 hour from San Diego Airport) with stay at the Rosarito Beach Hotel and administration of FMT at a medical clinic in close proximity to the hotel.
Whether you are driving or flying into San Diego, we arrange to pick you up at the airport or other landmark in San Diego and transport you directly to your lodging in Mexico.
5 days of medically supervised FMT treatment will be administered while in Mexico.
15 weeks of at-home FMT materials will be supplied for ongoing treatment.
Route of Administration
Our medical staff will help you determine whether a combination of enemas/liquid or capsules is the best route of administration for your child. This largely depends on their age and whether or not they can swallow capsules.
For the FMT product over the full 16 weeks of treatment, including medical consultation prior to, during, and following the retreat, it comes to a total of $12,500 USD.
Consult with Dr. Sandoval in Mexico: $250 USD
Transportation too and from Rosarito Beach Hotel: $250 USD (optional)
Lodging at Rosarito Beach Hotel is booked and paid for independent of FMT Solution. The cost will range between $500 – $1,000 for 4 nights depending on the booking type (ie. 1-bedroom vs 2-bedroom).
Book a Call.
To be considered to join one of our retreats, you must first have a phone call with one of our dedicated team members. This is a great opportunity to have any questions and/or concerns answered, so you can confidently make an informed decision!
As there is no cost to this call, please only schedule if you are serious about attending one of the scheduled retreats and in advance of the call, review all details and frequently asked questions on this site.
Rosarito Beach Hotel.
We have partnered with the Rosarito Beach Hotel to offer you and your family an exclusive lodging option. This hotel is perfectly designed for families with children as it includes pools, hot tubs, easy beach access, a playground with slides, swings and a merry go round. On the beach, locals offer pony rides and quad rentals for the more adventurous. The hotel is happy to help you in coordinating day trips to local attractions should you decide you want to see a little bit of Mexico.
The most critical component of your child’s medically supervised FMT treatment is adequate donor screening! Here at FMT Solution, we make this our #1 priority and follow all FDA and American Gastroenterology Association donor screening standards to ensure the highest quality product.
The donors undergo routine screening for both blood and stool borne pathogens. Before becoming a donor, they undergo this rigorous screening and then again on a routine basis to ensure all collected and processed materials are safe to be implanted.
- Complete Blood Count (CBC) & Comprehensive Metabolic Panel (CMP)
- HIV, type 1 and 2
- Hepatitis A virus IgM
- Hepatitis B surface antigen
- Hepatitis C virus antibody
- Treponema pallidum (Cascade with reflex to RPR)
- SARS-CoV-2 (IgG, IgM antibodies)
- C difficile toxin B by PCR
- Routine bacterial culture for enteric pathogens
- Ova and parasites
- PCR stool testing for beneficial fecal flora, pathogenic organisms, including bacteria, fungi, and parasites
- NEW screening following the death of an immunocompromised patient who received FMT treatment from a donor with Multidrug-Resistant Organisms (MDROs): ESBL, MRSA, VRE, CRE
In addition to extensive laboratory analysis, the donor’s medical background and health history is pivotal in determining whether or not they would make a suitable donor!
All donors are vaginally born, breastfed, active, physically fit and have either never received antibiotics or if they have, it has been many years in the past. Additionally, they eat a diverse omnivorous diet to ensure as much bacterial diversity as possible!
A basic screen of their medical history would include the following diseases:
- Chronic infectious disease(s)
- Known exposure to HIV or Viral Hepatitis
- Autoimmune disease(s)
- Gastrointestinal disease or symptoms
- Atopic disease(s)
- Metabolic disorders
- Mood disorders and Neuro-Atypical
- Neurodegenerative Disorder(s)
- Chronic pain syndrome
For confirmed retreat attendees, we can share your child’s specific donor profile. It will keep the donor anonymous but will give you more of an insight into more of their attributes beyond the lab results.
Frequently Asked Questions.
Questions always come up about events like this, and we want to save you some time by providing you with answers to the most common questions. Don’t hesitate to reach out with further questions by email (mailto: email@example.com – subject: FMT Retreat Questions).
Which conditions are commonly treated by FMT?
Both Health Canada and the FDA have only approved FMT for the treatment of C. difficile. However, there are several additional conditions that show compelling research including autism, IBD (Crohn’s, ulcerative colitis), IBS and chronic fatigue. There may be a role for FMT in patients with chronic constipation and neurodegenerative disease including Parkinson’s and multiple sclerosis.
Do you treat patients who do NOT have autism?
Yes, we do accept patients outside of the set retreat dates who have conditions that are likely to benefit from FMT. If you want to be considered to get treatment by FMT Solution for your particular condition, please send an email and we will get back to you shortly to set up a call if appropriate. (mailto: firstname.lastname@example.org – subject: FMT Retreat Questions)
I am a physician and want to refer patients. Can I learn more?
Yes, many of our patients come via referral or on the suggestion of their health care providers at home. We welcome referrals and collaboration so please send an email (mailto: email@example.com – subject: FMT Questions – Health Care Provider) and we would be happy to set up a call and support you in educating your patients.
How do I sign up for this retreat?
You will first have to speak with the medical team who will help you in deciding if you are a fit for this progressive therapy. If you are qualified, you will be required to pay a $5,000 USD deposit to hold your spot for a set date.
What age of children do you accept for these retreats?
The youngest children we accept are 3 years old, with no upper limit on age, meaning, we work with adult children with autism as well.
How many children do you accept at each retreat?
We currently accept 15 – 20 children per retreat to ensure the highest standard of care.
Can I speak with another family who attended a past retreat?
Although past families may go public in regards to their treatment results and experience in working with FMT Solution, we do not facilitate conversations between past patients and inquiring attendees as we take patient privacy very seriously.
Will Jason Klop speak with my doctor at home to determine if FMT is in my child's best interest?
Yes, we are happy to speak with your referring physician to answer any questions they may have as well as to collaborate on the best pre-FMT treatment strategy.
Will Jason Klop be at the retreat the entire time of my child’s treatment?
Yes, Jason Klop advises the Mexico licensed staff members throughout the retreat and is there to answer any of your questions.
Should the donor be the same age and sex as my child?
Some have hypothesized that age- and gender-matched donors may be advantageous, although currently there is no data to support this hypothesis.
When I go home with the “at home” FMT treatment materials, will there be ongoing support?
Yes, we are committed to ensuring you are able to complete the full 16 weeks of treatment without incident and will support you in collaboration with your medical team at home.
Should FMT be repeated after a certain length of time?
We don’t have enough data to suggest whether or not this is helpful or necessary in regards to FMT for the treatment of autism. With that said, Jason Klop does not believe repeat FMT treatments are necessary in the majority of cases. Where there may be an exception is if your child had to go on a strong and prolonged course of antibiotics and you saw a regression in their improvement since treatment.
How soon should we expect to see improvements in our child?
In some cases, improvements can be observed during the first week of treatment. However, as a rule of thumb, most children begin showing improvements in digestive symptoms at 5 weeks and improvement in autism-related symptoms at 8 weeks.
What adverse reactions should I expect while my child gets FMT treatment?
Some children experience mild to moderate hyperactivity and tantrums or aggression during the pre-FMT treatment.
Most children experience no adverse results when going through the treatment, although we have observed some children with increased hyperactivity during the first few days of treatment along with a temporary increase in gas.
How do you track progress and results?
We take a very objective approach to tracking patient improvement. We use the standardized Autism Treatment Evaluation Checklist (ATEC) prior to treatment, following treatment and then again at 6 months and 1 year following treatment. Additionally, we have parents track their child’s daily bowel movements using the Bristol Stool Form scale throughout treatment and then again for a two week period at 6 months and 1-year post-treatment.
I see some FMT clinics offering 10 enema treatments. Is this sufficient?
The most compelling data on the use of FMT for the treatment of autism was done over a period of 8 weeks of daily FMT dosing. Even with 8 weeks of treatment, there was a decline in the progress made upon stopping the FMT treatments. Hence, we choose to double the treatment window in hopes that it will improve the results patients experience compared to the Arizona State University study.
It is possible that some gains will be made in regards to digestive symptoms, but it is unlikely that sustained and meaningful gains will be made in the autism-related symptoms with only 10 enemas.
How many donors will my child receive over the course of 16 weeks of treatment?
Each attendee will receive a minimum of 2 donors throughout the course of treatment. This is similar to the protocol by Dr. Adams at Arizona State University.
Is having more donors better?
Jason Klop does not believe this is the case, especially when high quality extensively screened donors are used. The majority of the studies to date have only used a few donors per treated individual and still showed benefit. This includes the study done by Dr. Adams and his team at Arizona State University.
Where are your donors based?
FMT Solution has partnered with a private lab with American and Canadian donors. Although the retreats take place in Mexico, we do not use donors from Mexico.
Is FMT covered by insurance?
Insurance plans do not cover FMT for conditions outside of C diff. You may check with your insurance provider to see if you will be covered under extended insurance. However, we will NOT bill insurance directly. We will provide a detailed invoice at your request.
Are there any risks?
All medical interventions carry the potential for some risk. FMT is no different. However, the available research indicates that FMT has an excellent documented safety profile in the history of its use when adequate donor screening is performed. Complete informed consent will be given to attendees.
What if I don’t get better?
There is no way for us to guarantee that your child will experience gains with FMT. However, based on the available research and FMT Solution’s combined clinical experience, the success rates are very high!
Is Mexico safe?
Jason Klop has been to Mexico many times with his family to run the FMT retreats, dating back to early 2018. Neither he nor a patient he treated ever had any problems. Like anywhere in the world, it is important to be aware of your surroundings and make smart choices about where you go and when. As an example, you may not want to wander the streets in the middle of the night in an area you don’t know in a country whose language you don’t speak. Pretty common sense stuff!
Can I drink the water in Mexico?
It is not advised to drink the water in Mexico. The Rosarito Beach Hotel will provide several water bottles each day. If you need more, you can easily purchase more at a nearby convenience store or purchase them directly from the hotel.
Are there additional costs?
Yes, you will need to purchase a medical freezer to store your “at-home” FMT treatment in. A typical freezer is not suitable as it doesn’t get cold enough.
You are responsible for your transportation too and from San Diego, as well as any costs for food and entertainment you choose to participate in while in Mexico. Additionally, you are responsible for booking your lodging and pay the Rosarito Beach Hotel directly.
There may be some ancillary costs in regards to the pre-FMT treatment but those will be individual depending on what is advised and kept to a minimum.
I live in California, can I drive in to Mexico every day for treatment?
We do not advise that you do this. The border line ups can be at best unpredictable and we don’t want to increase the stress for you or for your child.
Will other therapies be offered (speech or occupational therapy)?
No, additional therapies are not suggested or offered during the one week of treatment in Mexico. It is our experience that a one week break from these types of therapies you typically receive at home is beneficial and is a great way to unwind. If you are taking any medication or require certain medical treatments, those will definitely be supported and accommodated!
Do I need to follow a specific diet?
No. We do not advocate for restrictive or limited diets. The goal upon completing FMT is to add as much diversity in the diet as possible and we will work with you to make that possible.
Do I need any specific lab testing prior to attending?
No, we do not require specific lab tests before attending. Having said that, many children have received many lab and stool tests and we are happy to review those prior to your child’s attendance and in collaboration with your physician to create a pre-FMT treatment plan.
Can I bring other children or adults?
Yes, we do not restrict the number of people who join you. If you need more rooms or an additional transport vehicle for your group, then that will be an expense you are responsible for. Most families come with 1 or 2 adults and in some cases 1 or 2 additional children who are siblings.
What if I can’t make those dates?
Keep an eye on this website for more dates to be released, or sign up to our email list to be the first to be notified of future dates. See the option to sign up below.
Is MTT different than FMT?
First, the terms:
MTT – Microbiota Transplant Therapy
FMT – Fecal Microbiota Transplant
Regardless of what the treatment is called, it is the same thing (human bacteria are transplanted from a screened donor into a patient). Most research studies refer to this treatment as FMT and so we use that terminology throughout our site. Some consider MTT to be different than FMT in that MTT is “processed” or “standardized.” As we standardize and concentrate our FMT material, it would be considered MTT under this description.
Will my child be anaesthetized or put to sleep during the treatment?
No. There is no need for anesthesia during the administration of the enema (enemas are only administered for children who are unable to swallow capsules). The enema is administered by an experienced nurse (see team description above) and takes all of 30 seconds to 1 minute to safely administer. Children often struggle to get away during the administration of the enema as it is an uncomfortable feeling, but this is typical and easily managed during this short period. They should experience no pain at all!
Where is the FMT administered?
The medical consult and administration of the FMT is all done at a medical clinic within close proximity to the hotel. Specifics of the clinic location are shared in advance of your arrival to Mexico.
Do you accept Canadians at your retreats?
No. At this time, Health Canada does not approve of Canadians receiving FMT treatments abroad, and until they expand the conditions approved for FMT, we are unable to assist Canadians with this treatment.